Eprotirome
Eprotirome Basic information
- Product Name:
- Eprotirome
- Synonyms:
-
- eprotirome
- N-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl]malonamic acid
- 3-((3,5-Dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
- Kb-2115
- Unii-958aq7B6R1
- Propanoic acid,3-[[3,5-dibroMo-4-[4-hydroxy-3-(1-Methylethyl)phenoxy]phenyl]aMino]-3-oxo-
- VPCSYAVXDAUHLT-UHFFFAOYSA-N
- KB2115 Exclusive
- CAS:
- 355129-15-6
- MF:
- C18H17Br2NO5
- MW:
- 487.14
- Mol File:
- 355129-15-6.mol
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Eprotirome Chemical Properties
- Boiling point:
- 596.3±50.0 °C(Predicted)
- Density
- 1.708
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO:84.0(Max Conc. mg/mL);172.43(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);61.58(Max Conc. mM)
Ethanol:63.5(Max Conc. mg/mL);130.35(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.03(Max Conc. mM) - form
- A crystalline solid
- pka
- 3.16±0.32(Predicted)
- color
- White to light yellow
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Eprotirome Usage And Synthesis
Uses
Eprotirome, is a liver-selective thyroid hormone receptor agonist.
in vivo
Eprotirome is a liver-selective thyroid hormone receptor agonist. Histological analysis of livers from mice treated with Eprotirome reveals that Eprotirome elicits a near complete elimination of lipid filled vacuoles that are characteristic of the livers from untreated control mice. Eprotirome treated mice also exhibit increased fasting glucose, but Eprotirome does not increase fasting insulin levels. Glucose levels of mice treated with Eprotirome continues to increase over time, leading to pronounced hyperglycemia by the end of the study. Temperature of mice treated with Eprotirome is decreased relative to untreated control mice[1].
EprotiromeSupplier
Shanghai Fuhe Chemistry Technology Co., Ltd.
- Tel
- 0086-21-67651709
- cfx759@hotmail.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
Shanghai Yu Ben Biotechnology Co., Ltd.
- Tel
- 021-61350663 15502154572
- 1639466865@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
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