Basic information Solubility in organics Uses storage Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  (R)-3-(Boc-Amino)piperidine

(R)-3-(Boc-Amino)piperidine

Basic information Solubility in organics Uses storage Safety Supplier Related

(R)-3-(Boc-Amino)piperidine Basic information

Product Name:
(R)-3-(Boc-Amino)piperidine
Synonyms:
  • CARBAMIC ACID, (3R)-3-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER
  • (R)-TERT-BUTYL-PIPERIDINE-3-YICARBAMATE
  • (R)-PIPERIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
  • (R)-3-AMINO-N-TBOC-PIPERIDINE
  • tert-Butyl [(3R)-piperidin-3-yl]carbamate, (3R)-3-[(tert-Butoxycarbonyl)amino]piperidine
  • Linagliptin interMediate B
  • Alogliptin Benzoate interMediate F
  • (R)-3-(Boc-amino)piperidine,97%
CAS:
309956-78-3
MF:
C10H20N2O2
MW:
200.28
EINECS:
685-989-2
Product Categories:
  • Piperidine Series
  • N-BOC
  • pharmacetical
  • Piperidine
  • Piperidines
  • Intermediates
  • 309956-78-3
Mol File:
309956-78-3.mol
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(R)-3-(Boc-Amino)piperidine Chemical Properties

Melting point:
121.0 to 125.0 °C
Boiling point:
304.8±31.0 °C(Predicted)
Density 
1.02±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in methanol and ethanol.
pka
12.37±0.20(Predicted)
form 
Solid
color 
White to Off-White
optical activity
[α]22/D +3.2°, c = 0.5 in DMF
BRN 
10662518
InChIKey
WUOQXNWMYLFAHT-MRVPVSSYSA-N
CAS DataBase Reference
309956-78-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,N
Risk Statements 
37/38-41-50
Safety Statements 
26-39-61-29-36
RIDADR 
3077
WGK Germany 
2
HazardClass 
9
PackingGroup 
HS Code 
29333990
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(R)-3-(Boc-Amino)piperidine Usage And Synthesis

Solubility in organics

Soluble in methanol and ethanol.

Uses

(R)-3-(Boc-amino)piperidine is Boc protected (R)-3-Aminopiperidine (A627920, Dihydrochloride salt) which has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.

storage

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Chemical Properties

White powder

Uses

(R)-3-(Boc-amino)piperidine is used as an organic chemical synthesis intermediate.

(R)-3-(Boc-Amino)piperidineSupplier

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