Basic information Safety Supplier Related

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER

Basic information Safety Supplier Related

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Basic information

Product Name:
3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER
Synonyms:
  • RARECHEM AL BF 0702
  • METHYL 3,4-DIHYDROXY-5-METHOXYBENZOATE
  • M3OMG
  • Benzoic acid, 3,4-dihydroxy-5-Methoxy-, Methyl ester
  • Methyl 3-methoxy-4,5-dihydroxybenzoate
  • 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER
  • Tryptophan-007
  • Bifendate-005
CAS:
3934-86-9
MF:
C9H10O5
MW:
198.17
Mol File:
3934-86-9.mol
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3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Chemical Properties

Melting point:
112-113 °C
Boiling point:
391.7±37.0 °C(Predicted)
Density 
1.337±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
8.21±0.23(Predicted)
form 
Solid
color 
Off-white to yellow
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Safety Information

HS Code 
2918999090
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3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Usage And Synthesis

Uses

Methyl 3,4-dihydroxy-5-methoxybenzoate is used as intermediates of biphenyl diesters.

Biological Activity

Methyl 3,4-dihydroxy-5-methoxybenzoate has antioxidant properties that protect neuronal cells from oxidative damage.

Synthesis

Methyl 3,4-dihydroxy-5-methoxybenzoate is synthesizede by esterified with gallic acid and then etherified with dimethyl sulfate.

in vivo

Methyl 3-O-methylgallate (M3OMG; 10 and 20 mg/kg, i.p., ) treatment mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities[1].

Animal Model:Fifty male Wistar rats (8-12 , 7-days old, 200-250 g)[1].
Dosage:10 and 20 mg/kg.
Administration:I.P. for 1 week.
Result:Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Preparation Products

Raw materials

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTERSupplier

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