Basic information Safety Supplier Related

SIGUAZODAN

Basic information Safety Supplier Related

SIGUAZODAN Basic information

Product Name:
SIGUAZODAN
Synonyms:
  • SIGUAZODAN
  • SK AND F-94836
  • SKF 94836
  • N-CYANO-N'-METHYL-N''-[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL]GUANIDINE
  • N-Cyano-Nmethyl-Nⅱ-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
  • Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
  • Siguazodan (SKF 94836)
  • [4R,(-)]-4,5-Dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]-4-methylpyridazin-6(1H)-one
CAS:
115344-47-3
MF:
C14H16N6O
MW:
284.32
Product Categories:
  • Cyclic Nucleotide related
Mol File:
115344-47-3.mol
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SIGUAZODAN Chemical Properties

Melting point:
268-268.9 °C(lit.)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >5 mg/mL, freely soluble
form 
solid
pka
13.71±0.60(Predicted)
color 
white
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3

MSDS

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SIGUAZODAN Usage And Synthesis

Uses

Siguazodan is a selective phosphodiesterase PDE III inhibitor and a potent inotropic agent.

Definition

ChEBI: 1-cyano-2-methyl-3-[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]guanidine is a pyridazinone.

Biological Activity

Phosphodiesterase inhibitor, selective for PDE3 (IC 50 = 117 nM).

SIGUAZODANSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
EMMX Biotechnology LLC
Tel
888-539-0666
Email
info@emmx.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Email
Sales@ATKchemical.com
Shanghai Changyu Medical Technology Co. Ltd.
Tel
+86-13301875428
Email
sales@changyuhe.com
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