ChemicalBook > CAS DataBase List > SIGUAZODAN

SIGUAZODAN

Product Name
SIGUAZODAN
CAS No.
115344-47-3
Chemical Name
SIGUAZODAN
Synonyms
SKF 94836;SIGUAZODAN;SK AND F-94836;Siguazodan (SKF 94836);SKF-94836,inhibit,Phosphodiesterase (PDE),SKF94836,Siguazodan,Inhibitor;N-Cyano-Nmethyl-Nⅱ-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine;N-CYANO-N'-METHYL-N''-[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL]GUANIDINE;Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-;4β-Methyl-4,5-dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]pyridazin-6(1H)-one;Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
CBNumber
CB6229034
Molecular Formula
C14H16N6O
Formula Weight
284.32
MOL File
115344-47-3.mol
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SIGUAZODAN Property

Melting point:
268-268.9 °C(lit.)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >5 mg/mL, freely soluble
form 
solid
pka
13.71±0.60(Predicted)
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris
Product number
1148
Product name
Siguazodan
Purity
≥99%(HPLC)
Packaging
10
Price
$122
Updated
2021/12/16
Tocris
Product number
1148
Product name
Siguazodan
Purity
≥99%(HPLC)
Packaging
50
Price
$510
Updated
2021/12/16
TRC
Product number
S497058
Product name
Siguazodan
Packaging
5mg
Price
$330
Updated
2021/12/16
Usbiological
Product number
256668
Product name
Siguazodan
Packaging
10mg
Price
$423
Updated
2021/12/16
ChemScene
Product number
CS-0014736
Product name
Siguazodan
Purity
>99.0%
Packaging
5mg
Price
$350
Updated
2021/12/16
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SIGUAZODAN Chemical Properties,Usage,Production

Uses

Siguazodan is a selective phosphodiesterase PDE III inhibitor and a potent inotropic agent.

Definition

ChEBI: 1-cyano-2-methyl-3-[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]guanidine is a pyridazinone.

Biological Activity

Phosphodiesterase inhibitor, selective for PDE3 (IC 50 = 117 nM).

SIGUAZODAN Preparation Products And Raw materials

Raw materials

Preparation Products

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SIGUAZODAN Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7267
Advantage
58
Shanghai Changyu Medical Technology Co. Ltd.
Tel
+86-13301875428
Email
sales@changyuhe.com
Country
China
ProdList
305
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000
Email
thinklifescience@163.com
Country
China
ProdList
19689
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58

115344-47-3, SIGUAZODANRelated Search:


  • SIGUAZODAN
  • SK AND F-94836
  • SKF 94836
  • N-CYANO-N'-METHYL-N''-[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL]GUANIDINE
  • N-Cyano-Nmethyl-Nⅱ-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
  • Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
  • Siguazodan (SKF 94836)
  • [4R,(-)]-4,5-Dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]-4-methylpyridazin-6(1H)-one
  • [4S,(+)]-4,5-Dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]-4-methylpyridazin-6(1H)-one
  • 4β-Methyl-4,5-dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]pyridazin-6(1H)-one
  • Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
  • SKF-94836,inhibit,Phosphodiesterase (PDE),SKF94836,Siguazodan,Inhibitor
  • 115344-47-3
  • C14H16N6O
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • G Proteins and Cyclic Nucleotides
  • Phosphodiesterase Inhibitors
  • Cyclic Nucleotide Metabolism
  • Cyclic Nucleotide related