tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Chemical Properties

Melting point:

130-132℃

Boiling point:

454.1±45.0 °C(Predicted)

Density 

1.182

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Very Slightly)

form 

Solid

pka

7.36±0.26(Predicted)

color 

Dark Yellow

Sensitive 

Air Sensitive

InChI

InChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)

InChIKey

RMULRXHUNOVPEI-UHFFFAOYSA-N

SMILES

N1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1

LogP

1.6-1.8 at 35℃ and pH7-9

Safety Information

HS Code 

2933599590

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Usage And Synthesis

Physical Form

Solid

Uses

4-(6-Amino-3-pyridyl)-1-Boc-piperazine (tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate) is used as an organic chemical synthesis intermediate.

Preparation

4- (6-Nitro-pyridin-3-yl)-piperazine-1 -carboxylic acid ie f-butyl ester and Pd/C in ethanol is stirred with an H2 balloon for 3 h. The product tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is obtained through purification.

Hazard

Causes skin irritation
Causes serious eye irritation
May cause respiratory irritation

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate(571188-59-5)Related Product Information

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