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(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

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(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Basic information

Product Name:
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Synonyms:
  • (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
  • [5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine
  • [5-Bromo-3-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-yl]amine
  • (R)-5-BroMo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylaMine
  • (R)-5-broMo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-aMine
  • Crizotinib Impurity 3
  • InterMediate Ⅰof Crizotinib (R)-5-broMo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine
  • 2-PyridinaMine, 5-broMo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-
CAS:
877399-00-3
MF:
C13H10BrCl2FN2O
MW:
380.04
EINECS:
700-798-7
Product Categories:
  • intermediate
  • 877399-00-3
Mol File:
877399-00-3.mol
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(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Chemical Properties

Melting point:
107.0 to 111.0 °C
Boiling point:
423.4±40.0 °C(Predicted)
Density 
1.643
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder to crystal
pka
5.55±0.10(Predicted)
color 
White to Light yellow to Light orange
InChI
InChI=1S/C13H10BrCl2FN2O/c1-6(11-8(15)2-3-9(17)12(11)16)20-10-4-7(14)5-19-13(10)18/h2-6H,1H3,(H2,18,19)/t6-/m1/s1
InChIKey
URFUZAZEKBBCEY-ZCFIWIBFSA-N
SMILES
C1(N)=NC=C(Br)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C
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Safety Information

HS Code 
2933.39.9200
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(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Usage And Synthesis

Chemical Properties

Pale yellow solid

Uses

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine is used in preparation of Crizotinib intermediate.

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