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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate

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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Basic information

Product Name:
(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
Synonyms:
  • (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
  • 2'Deoxy-2'fluoro-2'- Methyl- 3'5'-bis-o- (phenylcarbonyl) uridine
  • ((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-fluoro-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
  • URIDINE, 2'-DEOXY-2'-FLUORO-2'-METHYL-, 3',5'-DIBENZOATE, (2'R)-
  • 3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-Methyluridine
  • Sofosbuvir Intermediate 3
  • [(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl benzoate
  • 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine
CAS:
863329-65-1
MF:
C24H21FN2O7
MW:
468.43
EINECS:
807-766-2
Product Categories:
  • Sofosbuvir intermediate
Mol File:
863329-65-1.mol
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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Chemical Properties

Melting point:
256-258℃
Density 
1.42
pka
9.39±0.10(Predicted)
Water Solubility 
3.7mg/L
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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Usage And Synthesis

Uses

RO 2433 Dibenzoate is a related compound of RO 2433 (R637200), a deaminated metabolite of β-D-2''-Deoxy-2''-fluoro-2''-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.

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