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ChemicalBook >  Product Catalog >  Organic Chemistry >  Carboxylic acids and derivatives >  L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester

L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester

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L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester Basic information

Product Name:
L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
Synonyms:
  • L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
  • N-[(R)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-methylethyl ester
  • (S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
  • Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
  • N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl esterQ: What is N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl ester Q: What is the CAS Number of N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl ester
  • isopropyl (2S)-2-[[(R)-(2,3,4,5,6-pentafluorophenoxy)-phenoxy-phosphoryl]amino]propanoate
  • propan-2-yl (2S)-2-{[(R)-(2,3,4,5,6-pentafluorophenoxy)(phenoxy)phosphoryl]amino}propanoate
  • 380#Heterogeneous
CAS:
1337529-56-2
MF:
C18H17F5NO5P
MW:
453.3
Mol File:
1337529-56-2.mol
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L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester Chemical Properties

Boiling point:
442.6±55.0 °C(Predicted)
Density 
1.405±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
pka
-3.81±0.70(Predicted)
color 
White to off-white
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L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester Usage And Synthesis

Uses

Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].

References

[1] Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A.

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