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N-Chlorophthalimide

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N-Chlorophthalimide Basic information

Product Name:
N-Chlorophthalimide
Synonyms:
  • N-CHLOROPHTHALIMIDE
  • ncp
  • Phthalimidoyl chloride
  • phthalimide chloride
  • 2-chloro-1h-isoindole-1,3(2h)-dione
  • Chlorophtalimide
  • N-Chlorphthalimid
  • 2-Chloro-2H-isoindole-1,3-dione
CAS:
3481-09-2
MF:
C8H4ClNO2
MW:
181.58
EINECS:
222-459-8
Product Categories:
  • Chlorination
  • Halogenation
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • Synthetic Organic Chemistry
  • Carbonyl Compounds
  • Heterocycles
  • Cyclic Imides
  • Organic Building Blocks
  • 3481-09-2
Mol File:
3481-09-2.mol
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N-Chlorophthalimide Chemical Properties

Melting point:
188-198 °C (lit.)
Boiling point:
315.1±25.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
-3.53±0.20(Predicted)
color 
White to Almost white
InChIKey
WDRFYIPWHMGQPN-UHFFFAOYSA-N
CAS DataBase Reference
3481-09-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
1759
WGK Germany 
1
HazardClass 
8
PackingGroup 
II
HS Code 
29349990

MSDS

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N-Chlorophthalimide Usage And Synthesis

Chemical Properties

White to pale yellow powder

Uses

N-Chlorophthalimide may be employed in the synthesis of:

  • α-amino acetal
  • α-amino nitro compounds
  • vicinal diamine
  • α,β-unsaturated vicinal haloamino nitro compound
It may also be used as a chlorination reagent for the synthesis of 3-(methylthio)oxindoles.

General Description

N-Chlorophthalimide in anhydrous acetic acid serves as a useful oxidizing reagent for use in various direct titrimetric analyses. N-Chlorophthalimide can be synthesized by reacting phthalimide, t-butyl hypochlorite, water and t-butyl alcohol. It participates in the synthesis of 2-amino-3-benzoyl-α-(methylthio)phenylacetamide.

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