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5-METHOXY-2-NITROPHENOL

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5-METHOXY-2-NITROPHENOL Basic information

Product Name:
5-METHOXY-2-NITROPHENOL
Synonyms:
  • TIMTEC-BB SBB008609
  • 5-METHOXY-2-NITROPHENOL 98%
  • 5-METHOZY-2-NITROPHENOL
  • 5-METHOXY-2-NITROPHENOL
  • 3-HYDROXY-4-NITROANISOLE
  • phenol, 5-methoxy-2-nitro-
  • 2-Hydroxy-4-methoxynitrobenzene, 3-Hydroxy-4-nitrotoluene
  • 5-Methoxy-2-nitrophenol, 98% 1GR
CAS:
704-14-3
MF:
C7H7NO4
MW:
169.13
Product Categories:
  • Aromatic Phenols
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols
  • Building Blocks
  • C6 to C8
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
Mol File:
704-14-3.mol
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5-METHOXY-2-NITROPHENOL Chemical Properties

Melting point:
92-94 °C(lit.)
Boiling point:
298.4°C (rough estimate)
Density 
1.367
refractive index 
1.5830 (rough estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
6.95±0.13(Predicted)
form 
Powder or Crystals
color 
Yellow
CAS DataBase Reference
704-14-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29095000

MSDS

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5-METHOXY-2-NITROPHENOL Usage And Synthesis

Chemical Properties

yellow crystals or powder

Uses

5-Methoxy-2-nitrophenol is a reagent in the synthesis of conformationally constrained spirocycles, which are used as CCR1 antagonists. 5-Methoxy-2-nitrophenol is also used in the preparation of phenylsulfonyl aminophenoxybenzoates which can serve as EP1 receptor antagonists.

Synthesis Reference(s)

Synthetic Communications, 23, p. 343, 1993 DOI: 10.1080/00397919308009786

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