6-Cyano-2-naphthol Chemical Properties

Melting point:

165.5-170.5 °C (lit.)

Boiling point:

383.1±15.0 °C(Predicted)

Density 

1.28±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Ethanol, Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

8.57±0.40(Predicted)

color 

Pale Brown to Brown

CAS DataBase Reference

52927-22-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29269090

MSDS

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6-Cyano-2-naphthol Usage And Synthesis

Chemical Properties

Brown Crystalline Solid. 6-Cyano-b-naphthol [52927-22-7], 6-cyano2-hydroxynaphthalene, 6-hydroxy-2-naphthoic acid nitrile, Mr 169.17, mp 166 – 167℃ This nitrile is used as an intermediate for the production of liquid crystals and monoamino-oxidase-inhibiting naphthalene-2-oxyalkylamines, which are used as antidepressive agents.

Uses

Intermediate of Nafamostat mesilate (N210000).

Uses

Reactant for:

• Palladium-catalyzed reduction
• Nickel-catalyzed cross-coupling reactions
• Palladium-catalyzed Heck reactions

General Description

6-Cyano-2-naphthol (6CN2) is an aromatic alcohol that can be synthesized from 6-bromo-2-naphthol. It is a superphotoacid with the ground state pK_a^* value of 8.4 and excited state pKavalue of 0.2, respectively. 6CN2 protonates PANI-ES (polyaniline emeraldine salt) to form PANI-EB (emeraldine base), which shows enhanced conductivity. The proton-transfer kinetics and photophysical behavior of 6CN2 have been investigated.

6-Cyano-2-naphthol(52927-22-7)Related Product Information

• 2-Naphthol
• 2-Chloro-3-cyanopyridine
• Methylene dithiocyanate
• 1,1'-Bi-2-naphthol
• Terbinafine Hydrochloride
• Sodium cyanoborohydride
• ETHYL 2-CYANOACRYLATE
• 1-Naphthol
• ALPHA-NAPHTHOLBENZEIN
• 2-Naphthonitrile
• Cyano
• 2-CYANO-6-METHOXYNAPHTHALENE
• 6-Cyano-2-naphthol