Sodium trifluoroacetate Chemical Properties

Melting point:

205-207 °C (dec.) (lit.)

Density 

1.49 g/mL (lit.)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

H₂O: 1 M at 20 °C, clear, colorless

form 

Crystalline Powder

color 

White

Specific Gravity

1.49

PH

7 (H2O, 20℃)

Water Solubility 

625 g/L (25 ºC)

Sensitive 

Hygroscopic

Hydrolytic Sensitivity

6: forms irreversible hydrate

BRN 

3597949

Stability:

Hygroscopic

InChIKey

UYCAUPASBSROMS-UHFFFAOYSA-M

LogP

1.238 (est)

CAS DataBase Reference

2923-18-4(CAS DataBase Reference)

EPA Substance Registry System

Acetic acid, trifluoro-, sodium salt (2923-18-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

RIDADR 

2811

WGK Germany 

1

RTECS 

AK0250000

F 

3-10

Hazard Note 

Irritant/Hygroscopic

TSCA 

T

HazardClass 

6.1

PackingGroup 

II

HS Code 

29159080

MSDS

• Language:English Provider:Sodium trifluoroacetate
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Sodium trifluoroacetate Usage And Synthesis

Chemical Properties

Sodium trifluoroacetate is an organic metal compound with the chemical formula CF3COONa. It is a white crystalline powderr that easily absorbs moisture. This compound has the ability to add a trifluoromethyl group to halogenated aromatic hydrocarbons.

Uses

Sodium trifluoroacetate is used in acid catalyzed reactions. It is also used as an intermediate for active pharmaceutical ingredients (API). Further, it acts as a precursor for the trifluoromethylation of aldehydes using copper(I) halide as a catalyst.

Preparation

It can be obtained by reacting trifluoroacetic acid with sodium carbonate or sodium hydroxide.

Purification Methods

A possible contaminant is NaCl. The solid is treated with CF3CO2H and evaporated twice. Its solubility in CF3CO2H is 13.1% at 29.8o. The residue is crystallised from dilute EtOH, and the solid is dried in vacuum at 100o. [Hara & Cady J Am Chem Soc 76 4285 1954.] It can be precipitated from EtOH by adding dioxane, then recrystallising several times from hot absolute EtOH. Dry it at 120-130o/1mm. [Beilstein 2 IV 461.]

Sodium trifluoroacetate(2923-18-4)Related Product Information

• Diclofenac sodium
• Sodium benzoate
• Sodium chloride
• Trifluoroacetic acid
• Sodium hydroxide
• Sodium formate
• Sodium bicarbonate
• Sodium acetate
• Sodium carbonate
• Sodium gluconate
• Silver trifluoroacetate
• Trifluoroacetic anhydride
• Potassium trifluoroacetate
• Sodium thiophosphate
• Sodium thioglycolate
• 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT
• PALLADIUM(II) TRIFLUOROACETATE
• 2-Bromoethyl trifluoromethanesulphonate