Basic information Safety Supplier Related

Cyclosporin B

Basic information Safety Supplier Related

Cyclosporin B Basic information

Product Name:
Cyclosporin B
Synonyms:
  • Ala2-cyclosporine
  • Antibiotic S 7481F2
  • CYCLOSPORIN B
  • Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
  • (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Ala-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
  • Cyclosporin Impurity B
  • Cyclosporin Impurity 2(Cyclosporin B)
  • Cyclosporine IMpurity-B
CAS:
63775-95-1
MF:
C61H109N11O12
MW:
1188.58
Product Categories:
  • Intermediates & Fine Chemicals
  • Peptides
  • Pharmaceuticals
Mol File:
63775-95-1.mol
More
Less

Cyclosporin B Chemical Properties

Melting point:
149-152°C
alpha 
D20 -238° (c = 0.62 in chloroform); D20 -168° (c = 0.56 in methanol)
Boiling point:
1289.7±65.0 °C(Predicted)
Density 
1.019±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.32±0.70(Predicted)
color 
White to Pale Yellow
More
Less

Cyclosporin B Usage And Synthesis

Chemical Properties

Amorphous White Solid

Uses

Cyclosporin B is a minor analogue of the cyclosporin complex produced by a number of different fungal genera including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin B possesses immunosuppressant and antifungal activities but has been much less extensively investigated than the major analogue, cyclosporin A.

Uses

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Cyclosporin BSupplier

Fujian Kerui Pharmaceutical Co., Ltd. Gold
Tel
+86-591-83309157; 18505919179
Email
23115188@qq.com
Hefei fuya biotechnology co. LTD Gold
Tel
18096409024
Email
sales02@foreversyn.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com