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L-DICENTRINE

Basic information Safety Supplier Related

L-DICENTRINE Basic information

Product Name:
L-DICENTRINE
Synonyms:
  • (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
  • Cepharanthine α-base
  • Eximine
  • 10,11-Dimethoxy-7-methyl-6,7,7A,8-tetrahydro-5H-benzo[G][1,3]benzodioxolo[6,5,4-de]quinoline
  • 5H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7A,8-tetrahydro-10,11-dimethoxy-7-methyl-
  • Inchi=1/C20H21no4/C1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/H7-9,14H,4-6,10H2,1-3h
  • (R)-(-)-DICENTRINE
  • L-DICENTRINE
CAS:
28832-07-7
MF:
C20H21NO4
MW:
339.39
Product Categories:
  • Heterocycles
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
28832-07-7.mol
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L-DICENTRINE Chemical Properties

Boiling point:
480.7±45.0 °C(Predicted)
Density 
1.266±0.06 g/cm3 (20 ºC 760 Torr)
pka
6.65±0.20(Predicted)
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L-DICENTRINE Usage And Synthesis

Uses

A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion.

L-DICENTRINESupplier

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