N-Methyl-L-prolinol Chemical Properties

Boiling point:

67-69 °C12 mm Hg(lit.)

alpha 

-49.5 º (c=5, MeOH)

Density 

0.968 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.469(lit.)

Flash point:

146 °F

storage temp. 

2-8°C

form 

Liquid

pka

14.77±0.10(Predicted)

color 

Colorless to yellow

optical activity

[α]19/D 49.5°, c = 5 in methanol

BRN 

79851

CAS DataBase Reference

34381-71-0(CAS DataBase Reference)

NIST Chemistry Reference

N-Methyl-L-prolinol(34381-71-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-36-26

WGK Germany 

3

F 

8-10-23

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

N-Methyl-L-prolinol Usage And Synthesis

Uses

N-Methyl-L-prolinol is a reagent used in the synthesis of novel 4-hydroxytamoxifen analogs used as estrogen-related receptor γ (ERRγ) inverse agonists.

Chemical Properties

white to light yellow crystal powde

Uses

Precursor to phosphine ligands for catalytic asymmetric Grignard cross-coupling reactions.

N-Methyl-L-prolinol(34381-71-0)Related Product Information

• 2,2,6,6-Tetramethyl-4-piperidinol
• L-(+)-Prolinol
• Polyvinylpyrrolidone
• 1-Methylpyrrolidine
• Thiophanate-methyl
• Methyl acetate
• Methyl acrylate
• N-Methyl-2-pyrrolidone
• Kresoxim-methyl
• Methylparaben
• METHYLCYCLOHEXANOL
• METSULFURON METHYL
• Bensulfuron methyl
• Methyl
• SWAINSONINE
• GLYCYL-L-PROLINE
• Methyl bromide
• Parathion-methyl