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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE

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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Basic information

Product Name:
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE
Synonyms:
  • IBUPROFEN IMPURITY R
  • 1,1-Bis(p-isobutylphenyl)ethane
  • IBuprofen Impurity 18
  • Ibuprofen EP Impurity R
  • 1,1-Bis(p-isobutylphenyl)ethane(Ibuprofen EP Impurity R)
  • Ibuprofen EP Impurity R:Ibuprofen Impurity R
  • 1,1'-(Ethane-1,1-diyl)-4,4'-(2-meth
  • Benzene, 1,1'-ethylidenebis[4-(2-methylpropyl)-
CAS:
102120-87-6
MF:
C22H30
MW:
294.47
Mol File:
102120-87-6.mol
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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Chemical Properties

Boiling point:
174-184 °C(Press: 2-3 Torr)
Density 
0.924±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Acetonitrile (Slightly), Chloroform, Methanol (Slightly)
form 
Oil
color 
Colourless
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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Usage And Synthesis

Uses

1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.

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