2-(2-Hydroxyethyl)pyridine Chemical Properties

Melting point:

-8--7°C

Boiling point:

114-116 °C/9 mmHg (lit.)

Density 

1.093 g/mL at 25 °C (lit.)

vapor pressure 

1.16-14.1Pa at 25℃

refractive index 

n20/D 1.537(lit.)

Flash point:

199 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in Chloroform (Slightly), Methanol (Slightly).

form 

Liquid

pka

14.49±0.10(Predicted)

color 

Clear yellow to brown

PH

8-9 (100g/l, H2O, 20℃)

Water Solubility 

soluble

Sensitive 

Hygroscopic

BRN 

111205

LogP

0.38

CAS DataBase Reference

103-74-2(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyridineethanol(103-74-2)

EPA Substance Registry System

2-Pyridineethanol (103-74-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

2

RTECS 

UT2970450

F 

3

TSCA 

Yes

HS Code 

29333999

Hazardous Substances Data

103-74-2(Hazardous Substances Data)

MSDS

• Language:English Provider:2-(2-Pyridyl)ethanol
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-(2-Hydroxyethyl)pyridine Usage And Synthesis

Chemical Properties

clear yellow to brown liquid

Uses

2-Pyridineethanol is a metabolite of the anti-vertigo drug Betahistine (B324000).

Uses

2-(2-Hydroxyethyl)pyridine is a metabolite of the anti-vertigo drug Betahistine. It acts as a reagent for protection of the 5'-phosphate of nucleotides as 2-pyridylethyl (Pet) esters. It is used for carboxyl protection of amino acids. It is also used to cleave such groups as Boc and Fmoc, and also to hydrogenolysis. It was used to prepare mononuclear nickel(II) acetate.

General Description

2-(2-pyridyl)ethanol derivatives react with the aryl and alkenyl chlorides (palladium-catalyzed reactions) that result in the substitution of the chloro moieties with a 2-pyridylmethyl group.

2-(2-Hydroxyethyl)pyridine(103-74-2)Related Product Information

• 5-Amino-2-methylpyridine
• 2-(Hydroxymethyl)pyridine
• Sodium isethionate
• Clopidol
• 2,5-Dimethylpyridine
• Hydroxyethyl starch
• Pyridine
• 2-(2-Aminoethylamino)ethanol
• 2-(Ethylamino)ethanol
• Ethyl acetate
• Ethanol
• 2-(METHYLSULFONYL)ETHANOL
• 2-Chloro-5-chloromethylpyridine
• 2,6-Lutidine
• Hydroxyethyl Cellulose
• 4-Chlorobenzhydrol
• 2-Vinylpyridine
• N-Methyl-N,N-bis(2-pyridylethyl)amine