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(R)-4-Boc-Piperazine-3-carboxylic acid

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(R)-4-Boc-Piperazine-3-carboxylic acid Basic information

Product Name:
(R)-4-Boc-Piperazine-3-carboxylic acid
Synonyms:
  • 1-BOC-PIPERAZINE-2-(R)-CARBOXYLIC ACID
  • (R)-PIPERAZINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
  • (R)-1-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID
  • (R)-1-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
  • (R)-1-Boc-piperazine-2-carboxylic acid
  • (R)-4-Boc-Piperazine-3-carboxylicacid
  • N-Boc-piperazine-2-carboxylic acid
  • 1,2-Piperazinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2R)-
CAS:
278788-60-6
MF:
C10H18N2O4
MW:
230.26
Product Categories:
  • amino acids
  • pharmacetical
  • Piperaizine
Mol File:
278788-60-6.mol
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(R)-4-Boc-Piperazine-3-carboxylic acid Chemical Properties

Melting point:
243-247 ºC (DEC.)
Boiling point:
371.8±37.0 °C(Predicted)
Density 
1.193±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
form 
solid
pka
2.90±0.20(Predicted)
color 
White
CAS DataBase Reference
278788-60-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
HS Code 
2933599590
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(R)-4-Boc-Piperazine-3-carboxylic acid Usage And Synthesis

Uses

(R)-1-Boc-Piperazine-2-carboxylic Acid is used in preparation of pyridoisoquinolines as VAMT2 inhibitors for the treatment of hyperkinetic disorders.

(R)-4-Boc-Piperazine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

EtanolSodium hydroxideHydrochloric acidMethanolPalladium1,4-DioxaneDi-tert-butyl dicarbonateEthyldiisopropylamineBenzyl chloroformateL(-)-Camphorsulfonic acidPiperazine-2-carboxylic acid dihydrochloride(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride

(R)-4-Boc-Piperazine-3-carboxylic acidSupplier

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