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D-GALACTONO-1,4-LACTONE

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D-GALACTONO-1,4-LACTONE Basic information

Product Name:
D-GALACTONO-1,4-LACTONE
Synonyms:
  • 1,4-D-Galactonolactone
  • Galactonic acid, gamma-lactone, D-
  • GALACTONO-1,4-LACTONE, D-
  • GAMMA-D-GALACTONOLACTONE
  • D(-)-GALACTONIC ACID GAMMA-LACTONE
  • D-GALACTONO-1,4-LACTONE
  • D(-)-GALACTONO-GAMMA-LACTONE
  • D-GALACTONO-GAMMA-LACTONE
CAS:
2782-07-2
MF:
C6H10O6
MW:
178.14
EINECS:
220-484-9
Mol File:
2782-07-2.mol
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D-GALACTONO-1,4-LACTONE Chemical Properties

Melting point:
137°C
Boiling point:
467.9±18.0 °C(Predicted)
Density 
1.766±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
pka
12.06±0.60(Predicted)
color 
White to Off-White
LogP
-3.400 (est)
CAS DataBase Reference
2782-07-2(CAS DataBase Reference)
EPA Substance Registry System
D-Galactonic acid, .gamma.-lactone (2782-07-2)
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Safety Information

Safety Statements 
22-24/25
HS Code 
29322090
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D-GALACTONO-1,4-LACTONE Usage And Synthesis

Uses

D-Galactono-1,4-lactone was used in carbohydrate research as an elution compound for the purification process of exo-β-D-galactofuranosidase enzyme.

Definition

ChEBI: A galactonolactone derived from D-galactonic acid.

Purification Methods

Crystallise the lactone from EtOH, aqueous EtOH, MeOH or EtOAc. It is also purified by passage through a column of Amberlite IR-120 (H+ form), and the effluent and washings are then freeze-dried [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 67 1963, Academic Press]. The 5,6-O-isopropylidene-D-galactono-1,4-lactone is purified by chromatography (EtOAc) and has m 165-167o (from EtOH/hexane), and 167.5-168.5o (from Me2CO/*C6H6) [NMR: Copel & Stick Aust J Chem 31 1371 1978.] [Beilstein 18 III/IV 3026, 18/5 V 18.]

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