(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties

Boiling point:

133 °C/10 mmHg (lit.)

alpha 

+66°(23℃, c=1.15, CHCl3)

Density 

1.309 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.467(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

clear liquid

pka

13.07±0.20(Predicted)

color 

Colorless to Light yellow

Specific Gravity

1.32

optical activity

[α]23/D +66°, c = 1.15 in chloroform

BRN 

80588

CAS DataBase Reference

56881-90-4(CAS DataBase Reference)

Safety Information

WGK Germany 

3

HS Code 

2932209090

MSDS

• Language:English Provider:SigmaAldrich

(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Usage And Synthesis

Uses

(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:

• δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
• Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
• Botryolide B via esterification and ring-closing metathesis reaction.
• Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.

(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(56881-90-4)Related Product Information

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