Sanggenol L Chemical Properties

Boiling point:

662.2±55.0 °C(Predicted)

Density 

1.280±0.06 g/cm3(Predicted)

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

7.50±0.60(Predicted)

color 

Light yellow to yellow

Sanggenol L Usage And Synthesis

Uses

Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p

Definition

ChEBI: Sanggenol L is an extended flavonoid.

target

p65 | NF-kB | IkB | c-Myc | Caspase | IKK

References

[1] Won YS, Seo KI. Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor.?Food Chem Toxicol. 2020;138:111221. DOI:10.1016/j.fct.2020.111221
[2] Won YS, Seo KI. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells.?Nutrients. 2020;12(2):488. Published 2020 Feb 14. DOI:10.3390/nu12020488

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