Basic information Safety Supplier Related

sophoflavescenol

Basic information Safety Supplier Related

sophoflavescenol Basic information

Product Name:
sophoflavescenol
Synonyms:
  • sophoflavescenol
  • 3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-
  • 3,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
CAS:
216450-65-6
MF:
C21H20O6
MW:
368.38
Mol File:
216450-65-6.mol
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sophoflavescenol Chemical Properties

Melting point:
273-275 °C
Boiling point:
631.8±55.0 °C(Predicted)
Density 
1.359±0.06 g/cm3(Predicted)
storage temp. 
4°C, away from moisture and light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
7.03±0.40(Predicted)
color 
Yellow
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sophoflavescenol Usage And Synthesis

Uses

Sophoflavescenol is a potential cytotoxic agent against lung cancer A549 cells and colon cancer HCT116 cells.

in vivo

Sophoflavescenol exerts potent in?vivo?antitumor?activity?by tumor growth inhibition in the LLC tumor model as well as apoptotic?activity?by caspase-3 activation in HL-60 cells[1].

target

Caspase | ROS | NF-kB | NO | BACE | PDE

IC 50

BACE1; AChE; BChE; PDE5

sophoflavescenolSupplier

Shanghai Winherb Medical Technology Co., Ltd.
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021-38218169 13341702378
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winherb@126.com
MedChemexpress LLC
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021-58955995
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Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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tauto@tautobiotech.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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sales@reading-chemicals.com
Shanghai Aspire Biological Technology Co., Ltd.
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021-61317773
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sales@aspirebio.com