1,1'-Diacetylferrocene Chemical Properties

Melting point:

125-127 °C(lit.)

storage temp. 

Inert atmosphere,Room Temperature

form 

solid

Appearance

Brown to reddish brown Solid

Water Solubility 

Insoluble

InChI

InChI=1S/2C7H7O.Fe/c2*1-6(8)7-4-2-3-5-7;/h2*2-5H,1H3;

InChIKey

JNBIZDIDVCJECQ-UHFFFAOYSA-N

SMILES

[C]1([CH][CH][CH][CH]1)C(=O)C.[C]1([CH][CH][CH][CH]1)C(=O)C.[Fe] |^1:0,1,2,3,4,8,9,10,11,12|

CAS DataBase Reference

1273-94-5(CAS DataBase Reference)

NIST Chemistry Reference

1,1'-Diacetylferrocene(1273-94-5)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

36

WGK Germany 

3

RTECS 

LK0725666

HS Code 

29319090

Toxicity

mammal (species unspecified),LDLo,intratracheal,50mg/kg (50mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)KIDNEY, URETER, AND BLADDER: INCONTINENCE,"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 62, 1999.

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

1,1'-Diacetylferrocene Usage And Synthesis

Chemical Properties

dark orange to dark red powder

reaction suitability

core: iron
reagent type: catalyst

Synthesis

1) In a dry reaction vessel, anhydrous aluminum trichloride (0.1-0.18 moles) and methylene chloride (30-60 ml) were added and stirred until homogeneous. Subsequently, a mixed solution consisting of ferrocene (0.03-0.06 moles), methylene chloride (80-100 ml) and acetyl chloride (0.1-0.16 moles) was added slowly and dropwise. The reaction was first stirred at room temperature for 3-5 hours and then heated to reflux for 3-4 hours. Upon completion of the reaction, 70-100 ml of distilled water was slowly added to hydrolyze the aluminum trichloride, taking care to prevent splashing. After completion of hydrolysis, the reaction mixture was extracted with dichloromethane and the lower organic phase was separated in a separatory funnel. The upper aqueous phase was extracted three times with a small amount of dichloromethane and the organic phases were combined. The organic phase was dried with anhydrous magnesium sulfate, filtered to remove the desiccant and concentrated to give the crude product. The crude product was purified by aqueous recrystallization to give red needle-like crystals of 1,1'-diacetylferrocene in about 80% yield.

References

[1] Journal of the Chemical Society, Perkin Transactions 1, 2000, # 10, p. 1551 - 1557
[2] Patent: CN108530493, 2018, A. Location in patent: Paragraph 0032; 0038; 0044; 0049
[3] Patent: CN107226829, 2017, A. Location in patent: Paragraph 0022; 0026; 0030
[4] Journal of Organic Chemistry, 2015, vol. 80, # 19, p. 9563 - 9569
[5] Patent: CN104292274, 2017, B. Location in patent: Paragraph 0057

1,1'-Diacetylferrocene(1273-94-5)Related Product Information

• tert-Butylferrocene
• Ethylferrocene
• Hematite
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• Ferrocenecarboxylic acid
• Ferrocenecarboxaldehyde
• Acetylferrocene
• ETHYNYLFERROCENE
• Vinylferrocene
• pig iron
• 1,1'-DIBENZOYLFERROCENE
• CAST IRON
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• 1,1'-Diacetylferrocene