N-(3-Aminopropyl)morpholine Chemical Properties

Melting point:

−15 °C(lit.)

Boiling point:

224 °C(lit.)

Density 

0.987 g/mL at 25 °C(lit.)

vapor density 

4.97

vapor pressure 

11.5Pa at 20℃

refractive index 

n20/D 1.4761(lit.)

Flash point:

210 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

1000g/l

pka

10.30±0.10(Predicted)

form 

Liquid

color 

Colorless to Almost colorless

PH

12 (H2O, 20℃)

Water Solubility 

Soluble

Sensitive 

Air Sensitive

BRN 

105104

LogP

-1.076 at 20℃ and pH10.81-11.03

Surface tension

70.3mN/m at 1g/L and 20℃

Dissociation constant

10.08

CAS DataBase Reference

123-00-2(CAS DataBase Reference)

NIST Chemistry Reference

4-Morpholinepropanamine(123-00-2)

EPA Substance Registry System

4-Morpholinepropanamine (123-00-2)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

21-34-21/22-36/37-R34-R21/22

Safety Statements 

26-36/37/39-45-S45-S36/37/39-S26

RIDADR 

UN 2735 8/PG 2

WGK Germany 

2

RTECS 

QD7700000

F 

10-34

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29349990

Toxicity

LD50 orl-rat: 3560 mg/kg UCDS** 3/25/70

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-(3-Aminopropyl)morpholine Usage And Synthesis

Chemical Properties

Clear liquid

Uses

Fiber synthesis; chemical intermediate.

Uses

3-(4-Morpholinyl)propylamine is catalytic agent, petrochemical additive. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Definition

ChEBI: A member of the class of morpholines that is morpholine substituted by a 3-aminopropyl group a the N atom.

General Description

A colorless liquid with a faint, fishlike odor. Burns, but requires some effort to ignite. Corrosive to tissue. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Soluble in water.

Reactivity Profile

N-(3-Aminopropyl)morpholine behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Hazard

Strongly irritant to tissue.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

A corrosive material. Moderately toxic by several routes. A severe skin and eye irritant. Combustible. Can react with oxidizing materials. To fight fire, use alcohol foam, dry chemical. When heated to decomposition it emits toxic fumes of NOx,.

N-(3-Aminopropyl)morpholine(123-00-2)Related Product Information

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• 4-(3-Chloropropyl)morpholine
• 4-[3-(4-MORPHOLINO)PROPYL]-3-THIOSEMICARBAZIDE
• 3-(4-MORPHOLINO)PROPYL ISOTHIOCYANATE
• Furaltadone
• 3-HYDROXY-N-[3-(4-MORPHOLINYL)PROPYL]-2-NAPHTHALENECARBOXAMIDE
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• 3-Aminopentane
• 1,3-DIMORPHOLYL-2-PROPANOL
• 2-AMINO-N-(3-MORPHOLIN-4-YLPROPYL)BENZAMIDE
• 1-(3-MORPHOLINOPROPYL)-2-THIOUREA
• 5-MORPHOLINOMETHYL-3-[5-NITROFURFURYLIDENEAMINO]-2-OXAZOLIDINONE TARTRATE SALT