1-Boc-Pyrrolidine Chemical Properties

Boiling point:

80 °C/0.2 mmHg (lit.)

Density 

0.977 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.449(lit.)

Flash point:

187 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol

form 

Oil

pka

-1.28±0.20(Predicted)

color 

Clear Colorless

BRN 

4664750

CAS DataBase Reference

86953-79-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1-Boc-Pyrrolidine Usage And Synthesis

Chemical Properties

liquid

Uses

N-Boc-pyrrolidine may be used in the synthesis of the following:

• 2-aryl-N-boc-pyrrolidines
• scalemic 2-pyrrolidinylcuprates
• 2-alkenyl-N-Boc-pyrrolidines
• 1-deoxycastanospermine
• methylphenidate analogues
• (+)-elaeokanine A

Uses

1-Boc-pyrrolidine is a boc-protected cyclic amine used as a building block in the preparation of diastereomers by usually undergoing α'-lithiations and electrophilic substitution reactions.

General Description

N-Boc-pyrrolidine is an N-substituted pyrrolidine. It is reported that the reactivity of N-Boc-pyrrolidine towards C-H insertion reaction is 2000 times more than cyclohexane. It undergoes α-arylation in the presence of a palladium catalyst with high enantioselectivity.

1-Boc-Pyrrolidine(86953-79-9)Related Product Information

• 1-Methylpyrrolidine
• N-Vinyl-2-pyrrolidone
• Cyhalofop-butyl
• Povidone iodine
• Butyl acetate
• Buprofezin
• Butyl acrylate
• butyl rubber
• Butyl methacrylate
• N-Methyl-2-pyrrolidone
• Polyvinylpyrrolidone
• Pyrrole
• tert-Butyl carbazate
• tert-Butyl peroxybenzoate
• Pyrrolidine
• tert-Butanol
• 2-Butoxyethanol
• N-T-BOC-PYRROLE