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Hydroxybupropione

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Hydroxybupropione Basic information

Product Name:
Hydroxybupropione
Synonyms:
  • HYDROXYBUPROPION
  • HYDROXYBUPROPIONE
  • 1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE
  • 2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE
  • 1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine
  • 1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one
  • 1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
  • (±)-Hydroxybupropion solution
CAS:
92264-81-8
MF:
C13H18ClNO2
MW:
255.74
EINECS:
200-835-2
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Bupropion
  • Pharmaceuticals
Mol File:
92264-81-8.mol
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Hydroxybupropione Chemical Properties

Melting point:
121-123°C
Boiling point:
393.9±32.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
Flash point:
2℃
storage temp. 
-20°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
15.43±0.10(Predicted)
color 
White to Pale Yellow
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Safety Information

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36
Safety Statements 
16-36/37
RIDADR 
UN 1648 3 / PGII
WGK Germany 
2
HS Code 
3822900000
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Hydroxybupropione Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496

Definition

ChEBI: Hydroxybupropion is an aromatic ketone.

General Description

(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin? and Zyban?. This Certified Spiking Solution? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

HydroxybupropioneSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
Email
3bsc@sina.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
zhangsn@titansci.com
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
ChemStrong Scientific Co.,Ltd
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0755-66853366 13670046396
Email
sales@chem-strong.com
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Email
greensnown@163.com
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