O-METHYL-D-PROLINOL Chemical Properties

Boiling point:

61-62°C 40mm

alpha 

-2.4o (C=2% IN BENZENE)

Density 

0.932 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.446

Flash point:

45°C

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

10.01±0.10(Predicted)

form 

Liquid

color 

Clear colorless

optical activity

[α]20/D 2.4±0.3°, c = 2% in benzene

Sensitive 

Air Sensitive

BRN 

4229755

CAS DataBase Reference

84025-81-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

F 

3-10-34

HazardClass 

3

PackingGroup 

III

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

O-METHYL-D-PROLINOL Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

(2R)-2-(Methoxymethyl)-pyrrolidine is a useful synthetic intermediate. It can be used to prepare pyrazolo[3,4-d]pyrimidinylamino pyrrolecarboxamides for potential use as antitumor agents with reduced neutropenic side effects. It can be also used to synthesize heteroaryl pyrimidinylacetamides as A2A receptor antagonists.

O-METHYL-D-PROLINOL(84025-81-0)Related Product Information

• N-METHYL-D-PROLINOL
• O-METHYL-D-PROLINOL,O-METHYL-L-PROLINOL,O-Methyl-L-prolinol, SMP
• N-Methyl-DL-prolinol
• (R,R)-(-)-2,5-BIS(METHOXYMETHYL)-PYRROLIDINE
• N-Methyl-L-Prolinol HCl,N-METHYL-L-PROLINOL,1-METHYL-L-PROLINOL,(S)-2-Hydroxymethyl-1-methylpyrrolidine, N-Methyl-L-prolinol
• (S)-(-)-1-AMINO-2-(METHOXYMETHYL)PYRROLIDINE
• (R)-(+)-1-AMINO-2-(METHOXYMETHYL)PYRROLIDINE
• (R)-alpha,alpha-Diphenylmethylprolinol
• (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE