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Everolimus EP Impurity E

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Everolimus EP Impurity E Basic information

Product Name:
Everolimus EP Impurity E
Synonyms:
  • Everolimus EP Impurity E
  • 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 3-[(1R)-2-[(1S,3R,4S)-4-(formyloxy)-3-methoxycyclohexyl]-1-methylethyl]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-...
  • (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,-32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl formate
  • Formyl Sirolimus
  • Clobetasone Butyrate Impurity 8 (Clobetasone Butyrate EP Impurity H)
  • AP-417
CAS:
1237826-25-3
MF:
C52H79NO14
MW:
942.18
Mol File:
1237826-25-3.mol
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Everolimus EP Impurity E Chemical Properties

Boiling point:
974.9±75.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
pka
10.40±0.70(Predicted)
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Everolimus EP Impurity E Usage And Synthesis

Uses

42-O-Formyl Rapamycin is a derivative of Rapamycin (R124000). Rapamycin is a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. It is used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It has shown its efficacy against neurodegenerative diseases including Alzheimer''s and Parkinson''s.

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