2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER Chemical Properties

Melting point:

70-76 °C (lit.)

Boiling point:

230.5±23.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

soluble in Methanol

form 

powder to crystal

pka

7.60±0.10(Predicted)

color 

White to Almost white

Sensitive 

Moisture Sensitive/Lachrymatory

BRN 

606193

CAS DataBase Reference

14337-43-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

37/38-41-42/43-36/37/38

Safety Statements 

22-26-36/37/39-45-36

RIDADR 

UN 3335

WGK Germany 

3

F 

10-19-21

HS Code 

29280000

MSDS

• Language:English Provider:SigmaAldrich

2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER Usage And Synthesis

Chemical Properties

off-white solid

Uses

Ethyl 2-chloro-2-(hydroxyimino)acetate has been used:

• in the preparation of (+)-and (?)-Δ²-isoxazolines
• in the synthesis of CIP-AS (?), a chiral amino acid structurally related to glutamic acid, potential agonist at the ionotropic (±±)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA)-kainate receptors
• to generate ethoxycarbonylformonitrile oxide, in situ by treatment with sodium bicarbonate
• to prepare N-azirdinyloximes which on treatment with scandium triflate (418218) provide dihydro-oxadiazines

2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER(14337-43-0)Related Product Information

• 9-Fluorenylmethyl chloroformate
• ChloroMethyl Methyl Carbonate
• Chloromethyl chlorosulfate
• 2-chloroethoxyacetonitrile
• ETHYL (METHYLTHIO)ACETATE
• Acetaldoxime
• FORMALDOXIME HYDROCHLORIDE
• Methyl chloroacetate
• Ethyl chloroacetate
• 2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER
• Oxalyl chloride
• 2-Chloroethyl ethyl ether
• Chloroacetic acid