Thalidomide-NH-C6-NH2 TFA
Thalidomide-NH-C6-NH2 TFA Basic information
- Product Name:
- Thalidomide-NH-C6-NH2 TFA
- Synonyms:
-
- Thalidomide-NH-C6-NH2 TFA
- Pomalidomide Related Compound 11 Triflate
- 4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
- CAS:
- 2093386-51-5
- MF:
- C21H25F3N4O6
- MW:
- 486.45
- Mol File:
- 2093386-51-5.mol
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Thalidomide-NH-C6-NH2 TFA Chemical Properties
- solubility
- Soluble in DMSO
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Thalidomide-NH-C6-NH2 TFA Usage And Synthesis
Biological Activity
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Thalidomide-NH-C6-NH2 TFASupplier
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Shanghai Kaiwei Chemical Technology Co., Ltd.
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Thalidomide-NH-C6-NH2 TFA(2093386-51-5)Related Product Information
- Thalidomide-O-amido-C2-NH2
- 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
- -alkylC5-amine
- 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
- E3 ligase Ligand-Linker Conjugates 15
- Thalidomide-O-amido-C2-NH2
- Thalidomide-NH-C4-NH-Boc
- Thalidomide-NH-C4-NH2 TFA
- Thalidomide-NH-PEG2-C2-NH2 hydrochloride
- Thalidomide-NH-PEG2-C2-NH2 (TFA)