3-Ethoxypropylamine Chemical Properties

Melting point:

-70 °C

Boiling point:

136-138 °C (lit.)

Density 

0.861 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.418(lit.)

Flash point:

91 °F

storage temp. 

Flammables area

pka

9.79±0.10(Predicted)

form 

clear liquid

color 

Colorless to Almost colorless

PH

12 (100g/l, H2O, 20℃)

explosive limit

0.8-8.1%(V)

Water Solubility 

miscible

BRN 

1732287

InChI

1S/C5H13NO/c1-2-7-5-3-4-6/h2-6H2,1H3

InChIKey

SOYBEXQHNURCGE-UHFFFAOYSA-N

SMILES

CCOCCCN

CAS DataBase Reference

6291-85-6(CAS DataBase Reference)

NIST Chemistry Reference

1-Propanamine, 3-ethoxy-(6291-85-6)

EPA Substance Registry System

1-Propanamine, 3-ethoxy- (6291-85-6)

Safety Information

Hazard Codes 

C

Risk Statements 

10-22-34-35

Safety Statements 

26-36/37/39-45-36-28A-23-16

RIDADR 

UN 2734 8/PG 2

WGK Germany 

1

RTECS 

UI2700000

TSCA 

TSCA listed

HazardClass 

3

PackingGroup 

III

HS Code 

29221990

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B

MSDS

• Language:English Provider:3-Ethoxy-1-propanamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Ethoxypropylamine Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

It is employed as an intermediate used in the production of dyestuff and cosmetics. It is also used to partially open the rigid oxetane chain and to identify Hsp70 modulators.

Application

3-Ethoxypropylamine is mainly used for the synthesis of disperse red 90.

Synthesis

Synthesis method (from patent CN109369423B):
1. Acrylonitrile undergoes Michael addition with ethanol catalyzed by sodium ethoxide to yield 3-ethoxypropionitrile.
2. 3-Ethoxypropionitrile is hydrogenated under pressure in the presence of modified Raney Ni catalyst and liquid ammonia to give 3-ethoxypropylamine.

3-Ethoxypropylamine(6291-85-6)Related Product Information

• Ethyl 1-methylnipecotate
• 3-Ethoxypropylamine
• lifibrate
• 1,4-BUTANEDIOL BIS(3-AMINOPROPYL) ETHER
• Zidovudine
• 2',3'-O-Isopropylideneadenosine
• 1,4-Dioxa-8-azaspiro[4.5]decane
• 3-Isopropoxypropylamine
• Actinomycin D
• 6-AZAURIDINE 2',3',5'-TRIACETATE
• STRYCHNINE
• Ethyl nipecotate
• 10,11-Dimethoxystrychnine
• 3-CARBETHOXY-2-PIPERIDONE
• CYTOCHALASIN A
• 3-METHOXYETHOXYPROPYLAMINE
• ETHYL 3-AMINOBUTYRATE
• 1-PIPERIDINEPROPIONIC ACID ETHYL ESTER