Vildagliptin Chloroacetyl Nitrile (R)-Isomer Chemical Properties

Melting point:

64-67°C

Boiling point:

363.1±37.0 °C(Predicted)

Density 

1.27±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

-4.65±0.40(Predicted)

form 

Solid

color 

White to Pale Yellow

Vildagliptin Chloroacetyl Nitrile (R)-Isomer Usage And Synthesis

Uses

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.

Vildagliptin Chloroacetyl Nitrile (R)-Isomer(565452-98-4)Related Product Information

• Cyanuric acid
• 3-Amino-1-hydroxyadamantane
• Vildagliptin Carboxylic Acid
• 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)
• L-Proline, 4-chloro-, trans-
• 1,3,5,7-tetrahydroxyadamantane
• Amantadine
• N-acetic acid-1-aMino-3-adaMantanol
• Vildagliptin IMpurity 2 (Mixture of DiastereoMers)
• 1-Adamantanol
• Vildagliptin Impurity 25
• Dichloroacetyl chloride
• 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI)
• Vildagliptin iMpurity A-F
• pyrrolidine-2-carbonitrile 2,2,2-trifluoroacetate
• methyl L-prolinate
• Vildagliptin Impurity 6
• Vildagliptin Impurity 19