(-)-TEPHROSIN Chemical Properties

Melting point:

198° (218-220°)

Boiling point:

450.42°C (rough estimate)

Density 

1.2284 (rough estimate)

refractive index 

1.5300 (estimate)

storage temp. 

-20°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

pka

10.47±0.40(Predicted)

Safety Information

Hazard Codes 

N

Risk Statements 

50

Safety Statements 

61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

(-)-TEPHROSIN Usage And Synthesis

Uses

Tephrosin as a natural rotenoid obtained from Tephrosia vogelii and displays anticancer activity.

Definition

ChEBI: A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a a d methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities.

target

ROS | PARP | Autophagy | HSP (e.g. HSP90) | EGFR | Akt | ERK | Caspase | AMPK | mTOR

(-)-TEPHROSIN(76-80-2)Related Product Information

• HYDROXOCOBALAMIN
• Artemether
• beta-Sitosterol
• beta-Eudesmol
• MOSLOFLAVONE
• alpha-Cyperone
• hydroxygenkwanin
• Hydroxyecdysone
• 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• alpha-Terpineol
• (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one