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Parecoxib

Basic information Safety Supplier Related

Parecoxib Basic information

Product Name:
Parecoxib
Synonyms:
  • Parecoxib (free)
  • N-[4-(5-methyl-3-phenyl-oxazol-4-yl)phenyl]sulfonylpropanamide
  • N-((4-(5-Methyl-3-phenyl-2,3-dihydrooxazol-4-yl)phenyl)sulfonyl)propionaMide
  • N-(4-(5-Methyl-3-phenylisoxazol-4-yl)phenylsulfonyl)propionaMide
  • Parecoxib SodiuM IMpurity W
  • Valdecoxib Impurity J
  • SC 69124
  • Valus-P
CAS:
198470-84-7
MF:
C19H18N2O4S
MW:
370.42
EINECS:
803-261-6
Product Categories:
  • Inhibitors
  • ZY
Mol File:
198470-84-7.mol
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Parecoxib Chemical Properties

Melting point:
148.9-151°
Density 
1.264
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
5.08±0.10(Predicted)
color 
White to off-white
BRN 
8640266
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
63-48/22-51/53
Safety Statements 
36/37-61
WGK Germany 
3
RTECS 
TX1478700
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Parecoxib Usage And Synthesis

Uses

Anti-inflammatory; analgesic (cyclooxygenase COX-2 inhibitor).

Uses

Parecoxib is used in the combination with Telmisartan for the treatment of endometriosis. Parecoxib reduces hippocampal inflammation and improve short-term memory function through the inhibition of COX-2 expression in aged rats after splenectomy.

Definition

ChEBI: An N-acylsulfonamide resulting from the formal condensation of valdecoxib with propionic acid. It is a prodrug for valdecoxib.

ParecoxibSupplier

Shandong Chuangye Pharmaceutical Technology Co., Ltd. Gold
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TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
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Shanghai Hanhong Scientific Co.,Ltd.
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Shanghai G&K Biomedical Scientific Inc.
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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meilunui@163.com