Pyrimidinetetramine sulfate
Pyrimidinetetramine sulfate Basic information
- Product Name:
- Pyrimidinetetramine sulfate
- Synonyms:
-
- pyrimidinetetrayltetraamine sulphate
- PYRIMIDINE-2,4,5,6-TETRAMINE SULPHATE
- 2,4,5,6-TETRAAMINIOPYRIMIDINE SULFATE
- 2,4,5,6-TETRAAMINO-PYRIMIDINE SULFATE SALT
- 2,4,5,6-Tetraaminopyrimidine sulfate hydrate,98%
- 2,4,5,6-Tetraaminopyrimidine sulfate
- 6-TetraaMinopyriMidine sulfate
- PyriMidine-2,4,5,6-tetraaMine sulfate
- CAS:
- 5392-28-9
- MF:
- C4H10N6O4S
- MW:
- 238.22
- EINECS:
- 226-393-0
- Product Categories:
-
- Building Blocks
- C4 to C5
- Aromatics
- Chemical Synthesis
- Heterocyclic Building Blocks
- Heterocycle-Pyrimidine series
- FINE Chemical & INTERMEDIATES
- Amines
- (intermediate of methotrexate)
- Pyrimidines
- Building Blocks
- Heterocyclic Building Blocks
- Heterocycles
- Intermediates
- bc0001
- Mol File:
- 5392-28-9.mol
Pyrimidinetetramine sulfate Chemical Properties
- Melting point:
- >300 °C(lit.)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly, Heated), Water (Very Slightly, Heated)
- form
- Crystalline Powder
- color
- Ochre to brown
- Water Solubility
- slightly soluble
- BRN
- 3785189
- InChIKey
- MQEFDQWUCTUJCP-UHFFFAOYSA-N
- CAS DataBase Reference
- 5392-28-9(CAS DataBase Reference)
- EPA Substance Registry System
- Pyrimidinetetramine, sulfate (1:1) (5392-28-9)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-37/39-26-36
- WGK Germany
- 3
- RTECS
- UV9738000
- TSCA
- Yes
- HS Code
- 29335990
MSDS
- Language:English Provider:2,4,5,6-Tetraaminopyrimidine sulfate
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
Pyrimidinetetramine sulfate Usage And Synthesis
Chemical Properties
Light yellow crystal powder
Uses
2,4,5,6-Tetraaminopyrimidine Sulfate is an intermediate for the synthesis of the antitumor drugs methotrexate and fludarabine.
Purification Methods
Purify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.]
References
[1] SAUMYA SHUKLA. Toxic potential assessment of hair dye developer 2,4,5,6-tetraaminopyrimidine sulfate exposed under ambient UVB radiation.[J]. Toxicology and Industrial Health, 2024: 1-8. DOI:10.1177/07482337231209352.
[2] https://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_152.pdf
Pyrimidinetetramine sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrimidinetetramine sulfateSupplier
- Tel
- 24-24524889 18640309171
- 236415745@qq.com
- Tel
- 027-027-59322506 18071128681
- 1438082200@qq.com
- Tel
- 0831-6888461 15181138905
- sales@erealchem.com
- Tel
- 0512-68086196 15051406830
- 3228574886@qq.com
- Tel
- 0317-5296180 15533709196
- sale@enkepharma.com
Pyrimidinetetramine sulfate(5392-28-9)Related Product Information
- D-Glucosamine sulfate
- Aluminum sulfate
- Zinc sulfate heptahydrate
- SULFATE STANDARD
- Potassium persulfate
- Vanadyl sulfate
- Colistin sulfate
- Sodium sulfate
- Magnesium sulfate heptahydrate
- Ammonium sulfate
- Magnesium sulfate
- Barium sulfate
- Atropine sulfate
- Copper(II) sulfate
- SODIUM SULFATE
- sulfate
- 4,5,6-Triaminopyrimidine sulfate hydrate
- 2,4,5-Trifluorobenzonitrile