3-ALLYLOXY-1,2-PROPANEDIOL Chemical Properties

Melting point:

-100 °C

Boiling point:

142 °C28 mm Hg(lit.)

Density 

1.068 g/mL at 25 °C(lit.)

vapor pressure 

0.004 hPa (20 °C)

refractive index 

n20/D 1.462(lit.)

Flash point:

132 °C

storage temp. 

Store below +30°C.

solubility 

Completely miscible in water

pka

13.75±0.20(Predicted)

form 

Viscous Liquid

color 

Clear colorless to light yellow

PH

6.5-7.5 (1000g/l, H2O, 20℃)

Water Solubility 

163.2g/L at 25℃

BRN 

1701144

LogP

0.29 at 23℃

CAS DataBase Reference

123-34-2(CAS DataBase Reference)

EPA Substance Registry System

Glycerol 1-allylether (123-34-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

WGK Germany 

1

RTECS 

TY2700000

HS Code 

2909 49 80

Toxicity

LD50 orally in Rabbit: 5400 mg/kg LD50 dermal Rat 4300 mg/kg

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

3-ALLYLOXY-1,2-PROPANEDIOL Usage And Synthesis

Chemical Properties

clear colorless to light yellow viscous liquid

Uses

3-Allyloxy-1,2-propanediol is a useful synthetic intermediate. It is used to prepare doxorubicin analogs. It is also used to synhesize poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery.

Synthesis Reference(s)

Synthetic Communications, 24, p. 1959, 1994 DOI: 10.1080/00397919408010203

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