Basic information Safety Supplier Related

NEOBAICALEIN

Basic information Safety Supplier Related

NEOBAICALEIN Basic information

Product Name:
NEOBAICALEIN
Synonyms:
  • 2',5-Dihydroxy-6,6',7,8-tetramethoxyflavone
  • Skullcapflavon II
  • Skullcapflavone Ⅱ
  • scullcapflavone II
  • SKULLCAPFLAVONE II
  • NEOBAICALEIN
  • 4H-1-Benzopyran-4-one, 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-
  • Skullcapflavone II >=90% (LC/MS-UV)
CAS:
55084-08-7
MF:
C19H18O8
MW:
374.34
Product Categories:
  • Hexa-substituted Flavones
Mol File:
55084-08-7.mol
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NEOBAICALEIN Chemical Properties

Boiling point:
636.9±55.0 °C(Predicted)
Density 
1.375±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
6.81±0.40(Predicted)
color 
Yellow
InChI
InChI=1S/C19H18O8/c1-23-11-7-5-6-9(20)13(11)12-8-10(21)14-15(22)17(24-2)19(26-4)18(25-3)16(14)27-12/h5-8,20,22H,1-4H3
InChIKey
GMQFOKBGMKVUQZ-UHFFFAOYSA-N
SMILES
C1(C2=C(OC)C=CC=C2O)OC2=C(OC)C(OC)=C(OC)C(O)=C2C(=O)C=1
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NEOBAICALEIN Usage And Synthesis

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Schisandra chinensis.

Uses

Skullcapflavone II is derived from Scutellaria baicalensis, inhibitis ovalbumin-induced airway inflammation in a mouse model of asthma.

Definition

ChEBI: A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.

in vivo

Skullcapflavone II, a potential bradykinin antagonist, reduces the major pathophysiological features of allergic asthma, at least in part by acting on TGF-β1/Smad signaling pathways[3].

target

TGF-β/Smad | COX

NEOBAICALEINSupplier

Chengdu Herbpurify Co.Ltd. Gold
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2355253622; 18981954830
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2355253622@qq.com;
Chengdu Bioanseis Phytochemicals Co., Ltd. Gold
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13518187787
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632977132@qq.com
ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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shyysw007@163.com
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
Tel
021-38218169 13341702378
Email
winherb@126.com