5,7,8-TRIHYDROXYFLAVONE CAS#: 4443-09-8

5,7,8-TRIHYDROXYFLAVONE Basic information

Product Name:

5,7,8-TRIHYDROXYFLAVONE

Synonyms:

2-phenyl-5,7,8-trihydroxy-4h-1-benzopyran-4-on
2-phenyl-5,7,8-trihydroxy-4h-1-benzopyran-4-one
5,7,8-trihydroxy-flavon
NORWOGONIN
TRIHYDROXYFLAVONE, 5,7,8-
5,7,8-TRIHYDROXYFLAVONE
TRIHYDROXYFLAVONE, 5,7,8-(RG)
5,7,8-HYDROXYFLAVONE

CAS:

4443-09-8

MF:

C15H10O5

MW:

270.24

Product Categories:

Tri-substituted Flavones

Mol File:

4443-09-8.mol

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5,7,8-TRIHYDROXYFLAVONE Chemical Properties

Melting point:: 227-228 °C
Boiling point:: 528.4±50.0 °C(Predicted)
Density: 1.548±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 6.66±0.40(Predicted)
color: Yellow
InChI: InChI=1S/C15H10O5/c16-9-6-11(18)14(19)15-13(9)10(17)7-12(20-15)8-4-2-1-3-5-8/h1-7,16,18-19H
InChIKey: ZFKKRRMUPBBYRS-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)OC2=C(O)C(O)=CC(O)=C2C(=O)C=1
LogP: 1.970 (est)

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5,7,8-TRIHYDROXYFLAVONE Usage And Synthesis

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the tuberous root of Scutellaria baicalensis Georgi.

Uses

Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1]

Definition

ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -7 and -8.

target

VHR

References

[1] Choi HJ, et al. Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71. Biomol Ther (Seoul). 2016 Sep 1;24(5):552-8. DOI:10.4062/biomolther.2015.200

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