3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE Chemical Properties

Melting point:

229-230°C

storage temp. 

2-8°C

CAS DataBase Reference

33429-83-3(CAS DataBase Reference)

3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE Usage And Synthesis

Uses

Quercetin 3,4′-dimethyl ether (3,4′-Dimethylquercetin) is a dimethoxyflavone can be isolated from Combretum quadrangulare. Quercetin 3,4′-dimethyl ether overcomes TRAIL resistance by enhancing DR5 expression and has anti-tumor activity[1].

Definition

ChEBI: A dimethoxyflavone that is the 3,4'-dimethyl ether derivative of quercetin. Isolated from Combretum quadrangulare, it exhibits antineoplastic activity.

References

[1] Toume K, et al. Cycloartane triterpenes isolated from Combretum quadrangulare in a screening program for death-receptor expression enhancing activity. J Nat Prod. 2011 Feb 25;74(2):249-55. DOI:10.1021/np100784t

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