6-Aminoindole Chemical Properties

Melting point:

75-79 °C

Boiling point:

161-166°C 2mm

Density 

1.268±0.06 g/cm3(Predicted)

Flash point:

161-166°C/2mm

storage temp. 

-20°C

solubility 

soluble in Methanol

pka

18.23±0.30(Predicted)

form 

Crystalline Powder

color 

White to brown

Sensitive 

Air Sensitive

BRN 

112190

CAS DataBase Reference

5318-27-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Harmful

HazardClass 

IRRITANT-HARMFUL, KEEP COLD

PackingGroup 

III

HS Code 

29339900

MSDS

• Language:English Provider:6-Aminoindole
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

6-Aminoindole Usage And Synthesis

Chemical Properties

Solid

Uses

Reactant for preparation of:

• Inhibitors of mammalian target of rapamycin (mTOR ) protein
• Inhibitors of the AcrAB-TolC efflux pump
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
• Potent DNA-topoisomerase II poisons and anti-MDR agents
• Protein kinase C θ (PKCθ) inhibitors
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists
• Allosteric enhancers of the A3 adenosine receptor
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

6-Aminoindole(5318-27-4)Related Product Information

• Indole-3-acetic acid
• Indole-3-butyric acid
• Indometacin
• 5-AMINOINDOLE,5-Aminoindole;H-Indol-5-amine
• 4-Aminoindole;4-Indolamine
• 3-METHYL-6-NITROINDOLE
• 3-(DIMETHYLAMINOMETHYL)-6-NITROINDOLE
• 2-AMINOINDOLE, HYDROCHLORIDE
• 2-AMINOINDOLE-3-CARBOXYLIC ETHYL ESTER,ETHYL 2-AMINOINDOLE-3-CARBOXYLATE,2-AMINOINDOLE-3-CARBOXYLIC ACID, ETHYL ESTER
• 2H-INDOL-2-ONE, 6-AMINO-1,3-DIHYDRO-
• 5-AMINOINDOLE MONOHYDROCHLORIDE,5-AMINOINDOLE HYDROCHLORIDE
• 1-ACETYL-6-AMINOINDOLINE
• BOC-ABU-OH
• 5-Aminooxindole
• 1-BOC-5-AMINOINDOLE,5-Aminoindole, N1-BOC protected
• (r)-alpha-aminoindole-3-propanoicaci
• 1-BOC-6-AMINOINDOLE
• 6-Nitroindole