LOUREIRIN B
LOUREIRIN B Basic information
- Product Name:
- LOUREIRIN B
- Synonyms:
-
- LOUREIRIN B
- 1-Propanone,1-(4-hydroxyphenyl)-3-(2,4,6-triMethoxyphenyl)
- Loureirin B, 98%, from Dracaena cochinchinensis (Lour.) S. C. Chen
- 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one
- cochinchinenin B
- LOUREIRIN B USP/EP/BP
- ColouringB
- Loureirin B-RM
- CAS:
- 119425-90-0
- MF:
- C18H20O5
- MW:
- 316.35
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 119425-90-0.mol
LOUREIRIN B Chemical Properties
- Boiling point:
- 509.9±50.0 °C(Predicted)
- Density
- 1.177±0.06 g/cm3(Predicted)
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
- pka
- 8.06±0.15(Predicted)
- form
- powder
- color
- White
Safety Information
- Safety Statements
- 24/25
- HS Code
- 29145090
LOUREIRIN B Usage And Synthesis
Chemical Properties
White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the resin of the Dracaena frondosa tree.
Uses
Loureirin B is a component of traditional Chinese medicine which helps combat neurodegenerative diseases. Extracted from the red resin of Dracaena cochinchinensis S.C Chen, known as Dragon’s Blood.
in vivo
Loureirin B significantly improves the arrangement and deposition of collagen fibres, decreases protein levels of ColI, ColIII and α-SMA and suppresses myofibroblast differentiation and scar proliferative activity, in a rabbit ear scar model. Loureirin B effectively inhibits TGF-β1-induced upregulation of ColI, ColIII and α-SMA levels, myofibroblast differentiation and the activation of Smad2 and Smad3, in NS fibroblasts[3].
IC 50
PAI-1: 26.1 μM (IC50); KATP; ERK; JNK
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LOUREIRIN B(119425-90-0)Related Product Information
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- Vitamin B12
- β-Carotene
- Loureirin C
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- 2'-O-Methylisoliquiritigenin
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- 4,4'-DIHYDROXY-2-METHOXYCHALCONE
- ISOBAVACHALCONE
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- CYANIDIN CHLORIDE
- Hydroxysafflor yellow A
- Loureirin A
- LOUREIRIN B
- Pongapinone A