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13-Acetyl-9-dihydrobaccatin III

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13-Acetyl-9-dihydrobaccatin III Basic information

Product Name:
13-Acetyl-9-dihydrobaccatin III
Synonyms:
  • Cabazitaxel Impurity 55
  • 9-Dideacetyl baccatin VI
  • 2a,3,4,4a,5,6,9,10,12,12a-Decahydro-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol (2aR,4S,4aS,5R,6R,9S,11S,12S,12aR,12bS)-6,9,12b-triacetate 12-benzoate
  • 13-Acetyl-9-dihydrobaccatin III
  • 9-Dihydro-13-acetylbaccatinIII from Taxus canadensis
  • 9-DIHYDRO-13-ACETYL BACCATIN(9-DHB)
  • 7,9-Dideacetylbaccatin VI
  • 19-DHB
CAS:
142203-65-4
MF:
C33H42O12
MW:
630.68
Product Categories:
  • Miscellaneous Natural Products
Mol File:
142203-65-4.mol
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13-Acetyl-9-dihydrobaccatin III Chemical Properties

Melting point:
171-175°C
Boiling point:
704.5±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
12.61±0.70(Predicted)
form 
Solid
color 
White
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Safety Information

RIDADR 
1544
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
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13-Acetyl-9-dihydrobaccatin III Usage And Synthesis

Description

13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T. canadensis. It inhibits proliferation of P388 leukemia cells with an IC50 value of 20 μg/ml.

Uses

13-Acetyl-9-dihydrobaccatin-III is an apoptosis inducer.

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