3-Pyridylboronic acid Chemical Properties

Melting point:

>300 °C (lit.)

Boiling point:

308.8±34.0 °C(Predicted)

Density 

1.22±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Slightly soluble in methanol.

pka

4.00±0.10(Predicted)

form 

Powder, Crystals and/or Chunks

color 

White to yellow-orange

BRN 

471943

CAS DataBase Reference

1692-25-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi,C,F

Risk Statements 

36/37/38-22-34-11

Safety Statements 

36/37/39-3-26-45-16

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

IRRITANT, KEEP COLD

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Pyridylboronic acid Usage And Synthesis

Chemical Properties

Light Yellow Powder

Uses

Boronic acid derivatives and their binding affinities with diols.

Uses

suzuki reaction

Uses

3-Pyridylboronic acid is a reagent used for• ;Phosphine-free Suzuki-Miyaura cross-coupling reactions
1 ;Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation
2 ;N-arylation using copper acetylacetonate catalyst
3 ;Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes
4 Reagent use in Preparation of • ;New linear poly(phenylpyridyl) chains by Suzuki coupling
5 ;Oligopyridyl foldamers as mimics of a-helix twist
6 ;Many highly significant therapeutic enzymatic and kinase inhibitors and r

Synthesis Reference(s)

The Journal of Organic Chemistry, 64, p. 3846, 1999 DOI: 10.1021/jo9819279
Tetrahedron Letters, 43, p. 4285, 2002

3-Pyridylboronic acid(1692-25-7)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• Folic acid
• Citric acid
• Sulfasalazine
• Boric acid
• Zinc borate
• 2-Pyridineboronic acid
• Stearic acid
• 3-Aminopyridine
• 4-PYRIDYLBORONIC ACID,4-Pyridylboronic Acid (contains varying amounts of Anhydride)
• Pyridine
• Chromium picolinate
• 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 3-Pyridylboronic acid pinacol ester,3-PYRIDYLBORONIC ACID PINACOL ESTER
• 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 4-Pyridylboronic acid pinacol ester,4-PYRIDYLBORONIC ACID PINACOL ESTER
• 3-Pyridylacetic acid hydrochloride
• 2-Pyridinecarboxaldehyde
• Pyridine-2-carbonyl chloride hydrochloride
• ISONICOTINOYL CHLORIDE HYDROCHLORIDE