N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine Chemical Properties

Melting point:

212-214 °C

Boiling point:

546.95°C (rough estimate)

Density 

1.0738 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly, Heated), Methanol (Slightly, Heated)

form 

Solid

pka

3.58±0.10(Predicted)

color 

White to Off-White

N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine Usage And Synthesis

Description

Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid . It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid . Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of PEG-obestatin(Cys¹⁰, Cys¹³), a modified peptide hormone, in lean or diet-induced obese mice. Serum glycolithocholic acid levels increase with age in children.

Uses

A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.

Definition

ChEBI: The glycine conjugate of lithocholic acid.

N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine(474-74-8)Related Product Information

• 3ALPHA-HYDROXY-5BETA-CHOLAN 24-OIC ACID N-[CARBOXYMETHYL]AMIDE 3-SULFATE DISODIUM SALT
• SODIUM GLYCOCHOLATE HYDRATE, 98
• GLYCOCHOLIC ACID-13C1 (GLYCYL-1-13C)
• LITHOCHOLIC ACID
• Glycocholic acid
• GLYCODEOXYCHOLIC ACID
• GLYCODEOXYCHOLIC ACID SODIUM SALT
• GLYCOCHOLIC ACID SODIUM SALT
• Glycochenodeoxycholic acid sodium salt
• N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
• GLYCOURSODEOXYCHOLIC ACID, SODIUM SALT
• GLYCOLITHOCHOLIC ACID, SODIUM SALT
• Glycoursodeoxycholic acid
• glycohyodeoxycholic acid
• 5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA-DIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT
• 3ALPHA-HYDROXY-5BETA-CHOLAN-24-OIC ACID N-[CARBOXYMETHYL]AMIDE ETHYL ESTER
• GLYCOCHOLIC ACID, [GLYCINE-1-14C]
• GLYCOCHOLIC ACID-(GLYCINE-1-13C) MONOHYDRATE