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2-Chloro-4'-fluoroacetophenone

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2-Chloro-4'-fluoroacetophenone Basic information

Product Name:
2-Chloro-4'-fluoroacetophenone
Synonyms:
  • .alpha.-Chloro-p-Fluoroacetophenone
  • AKOS BBS-00004073
  • ALPHA-CHLORO-4-FLUOROACETOPHENONE
  • LABOTEST-BB LT00233195
  • 2'-CHLORO-4-FLUOROACETOPHENONE
  • 2-CHLORO-4'-FLUOROACETOPHENONE
  • 2-CHLORO-1-(4-FLUOROPHENYL)ETHANONE
  • 2-Chloro-4'-Fluoroacetophenone 2-Chloro-1-(4-Fluorophenyl)ethanone
CAS:
456-04-2
MF:
C8H6ClFO
MW:
172.58
EINECS:
207-256-4
Product Categories:
  • Acetophenone series
  • (intermediate of fluvastatin)
  • ACETYLHALIDE
  • 456-04-2
Mol File:
456-04-2.mol
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2-Chloro-4'-fluoroacetophenone Chemical Properties

Melting point:
47-50 °C(lit.)
Boiling point:
247°C
Density 
1.2752 (estimate)
vapor pressure 
1.9Pa at 27.1℃
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
form 
Flakes or Platelets
color 
Light yellow to yellow-beige
Water Solubility 
Insoluble in water.
Sensitive 
Lachrymatory
BRN 
637860
CAS DataBase Reference
456-04-2(CAS DataBase Reference)
NIST Chemistry Reference
«ALPHA»-chloro-para-fluoroacetophenone(456-04-2)
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Safety Information

Hazard Codes 
Xi,C,T
Risk Statements 
36/37/38-34-23/25-36
Safety Statements 
26-28-45-36/37/39-27
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
AM6550000
9-19
Hazard Note 
Corrosive/Lachrymatory
HazardClass 
8
PackingGroup 
II
HS Code 
29147000

MSDS

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2-Chloro-4'-fluoroacetophenone Usage And Synthesis

Chemical Properties

LIGHT YELLOW TO YELLOW-BEIGE FLAKES OR PLATELETS

Uses

1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole which was synthesized by condensing N-methyl-4-(methylthio)benzamidine with 2-chloro-4?-fluoroacetophenone.

General Description

2-Chloro-4′-fluoroacetophenone on condensation with N-methyl-4-(methylthio)benzamidine yields 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole.

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