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Pyridoxamine dihydrochloride

Basic information Safety Supplier Related

Pyridoxamine dihydrochloride Basic information

Product Name:
Pyridoxamine dihydrochloride
Synonyms:
  • PYRIDOXAMINE HCL
  • Pyridoxamine Dihydrochloride Monohydrate
  • 2-Methyl-3-hydroxy-4-aminomethyl-5-hydroxymethylpyridine dihydrochloride
  • Dyridoxamine hydrochloride
  • Pyridoxamine·2hydrochloride
  • vitamin B6dihydrochloride
  • Pyridoxamine dihydrochloride,4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride
  • Pyridoxamine dihydro
CAS:
524-36-7
MF:
C8H14Cl2N2O2
MW:
241.11
EINECS:
208-357-6
Product Categories:
  • Isolabel
  • Vitamins and derivatives
  • Aromatics
  • Bases & Related Reagents
  • Nucleotides
  • Aromatics Compounds
  • Pyridinium Compounds
Mol File:
524-36-7.mol
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Pyridoxamine dihydrochloride Chemical Properties

Melting point:
224-226 °C (dec.)(lit.)
Density 
1.4025 (rough estimate)
refractive index 
1.6100 (estimate)
storage temp. 
−20°C
form 
Powder or Solid
pka
pKa 3.31(H2O t = 25 I = 0.1)(Approximate)
color 
White to off-white to pale brown
Water Solubility 
Soluble in DMSO, water, or methanol /n
Merck 
7980
BRN 
3632748
CAS DataBase Reference
524-36-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
UV1230000
HazardClass 
IRRITANT
HS Code 
29333990

MSDS

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Pyridoxamine dihydrochloride Usage And Synthesis

Chemical Properties

White crystalline powder

Definition

ChEBI: A hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy.

Purification Methods

The amine salt is crystallised from hot MeOH. The free base crystallises from EtOH with m 193-193.5o [Harris et al. J Biol Chem 154 315 1944, J Am Chem Soc 66 2088 1944]. [Beilstein 22 IV 6064, 22/12 V 324.]

Pyridoxamine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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