Ethylene thiourea Chemical Properties

Melting point:

196-200 °C(lit.)

Density 

1.41~1.45

vapor pressure 

<1 hPa (25 °C)

refractive index 

1.5500 (estimate)

Flash point:

252 °C

storage temp. 

Store below +30°C.

solubility 

8g/l

form 

Powder

pka

15.01±0.20(Predicted)

color 

White

Odor

wh. to pale green crystals, faint amine odor

Water Solubility 

19 g/L (20 ºC)

Merck 

14,3803

BRN 

106275

Boiling point:

240°C (1010 hPa)

InChIKey

PDQAZBWRQCGBEV-UHFFFAOYSA-N

LogP

-0.67 at 20℃

CAS DataBase Reference

96-45-7(CAS DataBase Reference)

NIST Chemistry Reference

2-Imidazolidinethione(96-45-7)

IARC

3 (Vol. Sup 7, 79) 2001

EPA Substance Registry System

Ethylene thiourea (96-45-7)

Safety Information

Hazard Codes 

T

Risk Statements 

61-22-48/23/25-40

Safety Statements 

53-45

RIDADR 

2811

WGK Germany 

2

RTECS 

NI9625000

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29332990

Hazardous Substances Data

96-45-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 1832 mg/kg (Graham, Hansen)

MSDS

• Language:English Provider:1,3-Ethylenethiourea
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Ethylene thiourea Usage And Synthesis

Description

Ethylenethiourea, a thiourea derivative, is a rubber chemical. It has caused contact dermatitis mainly in rubber workers.

Chemical Properties

Ethylene thiourea is a white to light green, needle-like crystalline solid with a faint amine odor. It is very soluble in hot water;slightly soluble in cold water, methanol, ethanol, ethylene glycol, pyridine, acetic acid, and naphtha; and insoluble in acetone, ether, chloroform, and benzene.When heated to decomposition, ethylene thiourea emits toxic fumes of nitrogen oxides (NOx) and sulfur oxides (SOx).

Ethylene thiourea is available in the United States as crystals, as a powder, as an 80% dispersion of the powder in oil, or encapsulated in a matrix of compatible elastomers.

Uses

2-Imidazolidinethione is a pesticide used in production of fruits and vegetables. It is also used as a new contrast agent for MRI studies based on proton chemical exchange dependent saturation transfe r. 2-Imidazolidinethione is also a corrosion inhibitor due to the adsorption of the mol. species.

Uses

elastomer accelerator;chlorinated polyethylene (CPE) rubber vulcanizing accelerator agent.
Ethylene thiourea is used primarily as an accelerator for vulcanizing polychloroprene (Neoprene®) and polyacrylate rubbers. Neoprene rubbers are used almost exclusively in industrial applications，e.g.. for mechanical and automotive products, in wire and cable production, in construction，and in adhesives. Polyacrylate rubbers are used in products such as seals, o-rings, and gaskets for automotive and aircraft applications. Ethylene thiourea is used in the manufacture of ethylene-bisdithiocarbamate pesticides, such as Maneb®, Mancozeb®, Metiram®,and Zineb®.Ethylene thiourea is also used in electroplating baths, as an intermediate in antioxidant production, in dyes， pharmaceuticals，and synthetic resins. However, there is no evidence that the compound is used commercially for any of these purposes (IARC V.7, 1974; Sax, 1987).

Uses

Accelerator in the curing of polychloroprene (neoprene) and polyacrylate rubber; intermediate in the manufacture of antioxidants, insecticides, fungicides, dyes, pharmaceuticals, and synthetic resins

Definition

ChEBI: Ethylenethiourea is a member of imidazolidines.

General Description

White to pale green crystals or an off-white solid. Odorless when pure, but technical product may have an amine odor.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Ethlenethiourea may be sensitive to prolonged exposure to light. Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May react with acids to liberate hydrogen sulfide.

Hazard

Questionable carcinogen.

Health Hazard

Ethylene thiourea (ETU) is an antithyroid substance and animal carcinogen.

Fire Hazard

Ethylene thiourea is combustible.

Flammability and Explosibility

Non flammable

Contact allergens

Ethylene thiourea, a thiourea derivative, is a rubber chemical. It caused contact dermatitis mainly in rubber workers.

Potential Exposure

Ethylene thiourea is used extensively as an accelerator in the curing of polychloroprene (Neoprene) and other elastomers; as a vulcanizing accelerator in rubber processing; in electroplating baths. In addition, exposure to ethylene thiourea also results from the very widely used ethylene bisdithiocarbamate fungicides. Ethylene thiourea may be present as a contaminant in the ethylene bisdithiocarbamate fungicides and can also be formed when food containing the fungicides is cooked

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24- 48 h after breathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.

Carcinogenicity

Ethylene thiourea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, well-ventilated area away from strong oxidizers, acids, acidanhydrides, acrolein. Store in a refrigerator or a cool, dryplace. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

Purification Methods

Crystallise it from EtOH or amyl alcohol. [Beilstein 24 III/IV 22.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid anhydrides, and acrolein

Waste Disposal

Incineration in a furnace equipped with afterburner and scrubber.

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