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BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER

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BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Basic information

Product Name:
BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
Synonyms:
  • BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
  • METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE
  • N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
  • (4R)-1-BOC-4-FLUORO-L-PROLINE METHYL ESTER
  • (2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylic acid O1-tert-butyl ester O2-methyl ester
  • (2S,4R)-N-Boc-trans-4-fluoro-L-proline methyl ester
  • N-Boc-trans-4-fluoro-L-proline methyl ester
  • 1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
CAS:
203866-18-6
MF:
C11H18FNO4
MW:
247.26
Product Categories:
  • Asymmetric Synthesis
  • Building Blocks
  • Chemical Synthesis
  • Chiral Building Blocks
  • Fluorinated Building Blocks
  • Heterocyclic Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • Other Fluorinated Heterocycles
  • Pyrrolidines
Mol File:
203866-18-6.mol
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BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Chemical Properties

Melting point:
34-39 °C
Density 
1.16
Flash point:
110 °C
storage temp. 
2-8°C
form 
powder
optical activity
[α]22/D -80.0°, c = 1 in methanol
Water Solubility 
Insoluble in water.
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Safety Information

WGK Germany 
3
HS Code 
2933998090
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BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Usage And Synthesis

Uses

N-Boc-trans-4-fluoro-L-proline methyl ester is used to prepare (S)-2-[N-(N'-benzyl-(S)-4-fluoro-L-prolyl)amino]benzophenone by reacting with of 2-aminobenzophenone in the presence of potassium tert -butoxide.

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