1,5-DIHYDROXYANTHRAQUINONE Chemical Properties

Melting point:

279 °C (dec.)(lit.)

Boiling point:

342.92°C (rough estimate)

Density 

1.56 g/cm³

vapor density 

8.3 (vs air)

refractive index 

1.5430 (estimate)

storage temp. 

-20?C Freezer

pka

6.42±0.20(Predicted)

Merck 

14,689

BRN 

1881718

CAS DataBase Reference

117-12-4(CAS DataBase Reference)

EPA Substance Registry System

Anthrarufin (117-12-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-36/37

WGK Germany 

3

RTECS 

CB6630000

TSCA 

Yes

HS Code 

29146990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,5-DIHYDROXYANTHRAQUINONE Usage And Synthesis

Chemical Properties

Yellow to Green Solid

Uses

1,5-Dihydroxyanthraquinone is an anthraquinone derivative with suppressive effects against nitric oxide (NO) synthase. Potential antimalarial agent. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 protei nase.

Uses

Important intermediate in the manufacture of alizarin and indanthrene dyestuffs. Forms insoluble Ba and Ca lakes; has been proposed as analytical reagent for the detection of Ca.

Uses

1,5-Dihydroxyanthraquinone (anthrarufin) is an important intermediate for manufacturing disperse blue dyes. It is the key intermediates for manufacturing disperse blue dyes via dinitrodihydroxyanthraquinone and vat dyes via diaminoanthraquinones.

Definition

ChEBI: A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 5.

Purification Methods

Purify anthrarufin by column chromatography on silica gel with CHCl3/Et2O as eluent, followed by recrystallisation from acetone. Alternatively recrystallise it from glacial acetic acid [Flom & Barbara J Phys Chem 89 4489 1985]. [Beilstein 7 III 2359, 8 IV 3268.]

1,5-DIHYDROXYANTHRAQUINONE(117-12-4)Related Product Information

• Daunorubicin
• ANTHRACENE BLUE SWR
• 1,5-dimethoxyanthraquinone
• ISLANDICIN
• 1,5-DIHYDROXY-4,8-DINITROANTHRAQUINONE
• 4,8-diamino-1,5-dihydroxyanthraquinon
• Esorubicin
• 1-amino-4,5,8-trihydroxyanthraquinone
• HELMINTHOSPORIN
• 1,5-DIPHENOXYANTHRAQUINONE
• Menogaril
• 1,5-dichloro-4,8-dihydroxyanthraquinone
• Carubicin
• 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
• Adriamycin
• CYNODONTIN
• DISPERSE BLUE 26
• CI 58610